About Us

A Software Company

Cancer Informatics

Formed March 2015

Open for Business

Contact Us

Adding Clients & Partners

Technology Licensed from The Ohio State University

MatchTx is a Big Data healthcare analytics software company with unique patent-pending technology. The solution enables matching patients to cancer drugs and clinical trials with novel methods to find best matches using genetic, clinical, and outcome data. The technology was licensed exclusively from partner The Ohio State University. MatchTx was awarded a competitive $125,000 grant from the Third Frontier Program of the State of Ohio. Initial equity investment enabled commercial product development and clinical data validation of the technology (proven out in peer-reviewed publications on both cancer cell-lines and cancer patient studies).




Growing our business

Our cloud-hosted product platform and and our team of healthcare IT software developers and data scientists are ready work with you on your project, your clinical trial, or your patients.


Pilot Project Studies

Our solution is now commercially available. MatchTx is taking on a limited number of qualified cancer patient data studies in a shared risk manner- contact us so that we can begin working together.



We have not lost our academic roots. If you have data sets, software tools, or grant opportunities, please contact us.

MatchTx, LLC

Matching Therapeutics to Cancer Patients™

Personalizing Precision Medicine using Deep Genetic Signatures™

Founding Year


Jeff Wilt (CPA), COO/CFO – Over 30 years as senior executive managing healthcare software companies. Successfully led development, business operations, and nationwide sales of healthcare software that integrated with EMR systems. Jeff has a personal stake in MatchTx, having recently lost a close family member (daughter) to cancer at the James Cancer Center, OSU. Wilt is dedicated to lead day to day business and sales operations and provide business management expertise around finance and project management.

Dr. James Chen (MD), the inventor of the technology, is Assistant Professor in Biomedical Informatics and in Internal Medicine at OSU and a translational oncologist with extensive bioinformatics experience. He is also a Founder and serves as Director of Precision Medicine of MatchTx. He is involved in all aspects of developing and commercializing the technology. Dr. Chen was recently named Chair-Elect for the ASCO Health Information Committee and ASCO Liaison to the Global Alliance for Genomics and Health.

Dr. Jeff Spitzner, CEO, has over 20 years’ experience as a founder and executive of eight scientific software and bio-technology companies that contributed over $30 Million to the Columbus, OH community. Spitzner won 2011 Executive of the Year Innovation Award and has experiences in equity fundraising, product vision and management, strategic marketing, sales management, business development, and executive leadership. He raised millions of dollars in equity investment for previous ventures. His businesses sold clinical research solutions to the same set of organizations targeted for MatchTx. Jeff received his Ph.D. (molecular cancer research and bioinformatics) from The Ohio State University, then did post-doctoral work at MIT. Spitzner led pioneering technology development and commercialization efforts in areas including bioinformatics and human genome research. Spitzner also partnered with Ohio State and Signet Enterprises to facilitate commercialization of the University’s collaborative Healthcare IT platform as Signet Accel. As CEO, he  manages the growth and business activities of MatchTx.

Software Development, Data Sciences, and Customer Support.

MatchTx has assembled an excellent team to grow and support the product and our customers. Please contact us if you wish to become part our great team.



311 Kendall PL
Columbus, OH 43205


Please email us to arrange a call or web meeting

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