MatchTx Applications

 

Multiple genes and variants (Mut & WT) contribute to tumor drug response. FIND THEM ALL and apply the Deep Genetic Signatures™

MatchTx software and algorithms address key needs in utilizing clinical, genetic, and outcome data to make precise predictions about patients, samples, and oncology drugs. MatchTx delivers actionable sets of genetic biomarkers for best-matched patient cohorts.
Plan your research studies, validate clinical trials outcomes, predict drug treatment outcomes.

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CLINICAL TRIALS & DRUG REPOSITIONING

CLINICAL TRIALS & DRUG REPOSITIONING for Patient Population (biomarker) Segments

CLINICAL TRIALS & DRUG REPOSITIONING for Patient Population (biomarker) Segments

  • Find sets of genetic markers (profiles) that distinguish between positive and negative responders (retrospective clinical studies)
  • Cell-line studies: genetic profiles for response
  • Use validated biomarker profiles to set up clinical trial protocols using patient segmentation
  • Analyze Phase II clinical trial results for patient exclusion in Phase III for contraindicated biomarkers
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CANCER GENOMICS RESEARCH

  • Genetic Targeting/Profiles of drug leads
  • Tumor characterization
  • Drug-specific tumor databases.
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CANCER GENOMICS RESEARCH

CANCER GENOME RESEARCH

BIOMARKER DISCOVERY & VALIDATION

BIOMARKER DISCOVERY & VALIDATION

BIOMARKER DISCOVERY & VALIDATION

  • Identify ALL the genetic biomarkers associated with drug response (mutations and wild type)
  • Validate genomic biomarkers
  • Develop companion diagnostics
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DRUG DEVELOPMENT

  • Confirm genetic on-target activity of leads
  • Genes whose mutation status impacts drug response
  • Identify other tumor types or drugs with similar target biomarker profiles 
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DRUG DEVELOPMENT

DRUG DEVELOPMENT APPLICATIONS